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Dominant adaptive immune cell infiltration composed of B cells, CD4 + T cells and CD8 + T cells or ectopic lymphoid follicle-like structures were observed in the LSGs of patients with pSS

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However, the skin barrier limits the transdermal absorption rate, and simple topical application is difficult to significantly increase the oxidation rate of fatty acids throughout the body or locally

When delivered intravenously, glutathione bypasses the digestive system and directly enters the bloodstream, allowing almost 100% bioavailability