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With nicotine use and abuse, vasoconstriction in oral tissues can lead to reduced bleeding upon probing which may give a false clinical indication

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(2) The Rebate Report for the applicable period beginning October 1, 2023, will be issued no later than December 31, 2025

In Table 42, we expand upon the hypothetical example described in Table 41 and summarize how we would calculate national and regional update factors following the methodology specified in 425.652(b)(2) but using the adjusted regional and national expenditures for the performance year for each enrollment type in place of the original values

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