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3b) as well as three other nicotine metabolites (Figure S4), suggesting that they were consuming more total nicotine (e-cigarettes + conventional cigarettes) than those not currently using e-cigarettes

Studies using a variety of different puffing regimes showed no increase in the formation of toxicants, and clinical studies in which participants could use the product freely demonstrated reductions in exposure to toxicants approaching 95% of the reductions seen in smokers who quit for the duration of the study

According to the data, the popularity of RYO cigarettes increased significantly from 2011 to 2016

Condition: Very good vintage condition with age-appropriate wear consistent with decades of careful use

Vapor Instead of Smoke: HEETS and TEREA heat tobacco without combustion, emitting an aerosol vapor with fewer toxic byproducts