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Taken together with data from a recent survey-based study indicating that some smokers find NPs appealing and may percieve them as a reduced-risk product 49 , and positive subjective responses from smokers during an NP nicotine PK study 48 , these products may act as a nicotine source that provides smokers with a satisfactory and complete alternative to conventional cigarettes

Additional support was from the National Affiliate of the American Heart Association (12SDG12050473 to D.J.K.), the David and Helen Boone Foundation Research Fund (D.J.K.), an Early Career Development Award from the Central Society for Clinical and Translational Research (D.J.K.), the University of Toledo Women and Philanthropy Genetic Analysis Instrumentation Center (D.J.K

Food and Drug Administration (FDA) has concluded that it contains fewer toxic chemicals than cigarette smoke

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