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Below are the three most common combinations and why they make sense

There are also cases of the higher range of 500mcg being used twice daily

Furthermore, the TEAE of injection-site reactions aligns with results from previous clinical trials with approved GLP-1 receptor agonists [24] and PCSK9-antibody inhibitors [25]

Dose Range: 0.64.5 mg weekly with gradual titration every 2 weeks

Overall, this work proposed a convenient, safe, and effective rectal drug delivery strategy, providing a new candidate for the prevention and treatment of radiation-induced proctitis, and also providing a reference for the design of multifunctional local delivery systems in radiation-associated tissue injury