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Legal Status and Dosage: MT1 is approved by the FDA for sunless tanning and treating erythropoietic protoporphyria as a subcutaneous implant

A pigmentation endpoint accompanied by nausea, appetite changes, yawning, erection-related effects, or central melanocortin signals is not the same research question as a relatively selective MC1R photoprotection model

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When evaluating weight-loss claims, it helps to think in terms of systems rather than slogans