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Structure of alphaketoglutarate dehydrogenase complex This 4 to 10 mega Dalton supramolecular complex is organized around a polyhedral form of a cubic core of 24/60 lipoate bearing dihydrolipoyl succinyltransferase E2 subunits (8 trimers) arranged with octahedral (432) symmetry [5] associated with non covalently attached multiple copies of dihydrolipoamide E1k and dihydrolipoamide E3K individually held via its E1/E3 binding domains which serve as scaffolds for the E2 core

It plays a vital role in regulating blood sugar levels and overall metabolism by performing several key functions: Stimulating Insulin Secretion : When you eat, your blood sugar levels rise

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