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Its depletion, driven by ageing, suboptimal nutrition, or chronic oxidative stress, compromises detoxification pathways and accelerates cellular ageing, manifesting as skin dullness, fatigue and systemic dysfunction. Mechanism of glutathione therapy According to Dr Viral Desai, administered via intravenous (IV) infusion, intramuscular injection, or oral supplementation, glutathione therapy augments systemic antioxidant capacity