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Proven cardiovascular benefits in appropriate patients
32 Additionally, the impact on skeletal muscle mass and quality will be important to establish given the potential for sarcopenia in this HF population
washout Timeline 1: Immediate switch (most common) Day 0: Last Wegovy injection Day 7: First Zepbound injection (2.5 mg or higher per provider instruction) Day 14: Second Zepbound injection Weeks 5, 9, 13, etc.: Dose increases per titration schedule This approach maintains continuous GLP-1 receptor agonism
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