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Tobacco causes 6% of all world deaths and about 3% of global number of diseases

Additionally, the study was powered to detect small effects for the primary analysis, so could have been underpowered to detect interaction effects for the secondary research questions

Under these assumptions, 80% of people with lung cancer are smokers, so 16 is the correct answer

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However, cigarillos had two distinct subgroups of brands, with the sugar content in one subgroup being similar to little cigars (i.e., low), while sugar content in the other group was as high as in cigarettes (Figure 1)