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However, there are two distinct types of youth ENDS users: those who, in the absence of ENDS, would have taken up combustible tobacco use and those who would have remained nicotine-abstinent

He hobbled to the bedroom, clutching his distended stomach, and returned carrying a dog-eared Bible with grainy images of his tumor-filled colon tucked inside

Stress conditions, such as DNA damage, hypoxia, nutrient deprivation or oncogene activation, lead to the inhibition of MDM2 and/or direct modification of p53, resulting in the stabilisation and thus activation of the p53 protein