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Obesity, insulin resistance and fatty liver may further amplify this cycle by increasing inflammatory signaling, altering bile-acid metabolism and reducing metabolic reserve
Lim HW, Kohli I, Granger C, Trullas C, Piquero-Casals J, Narda M, et al
Prior to the weighting of covariates, GLP-1 receptor agonist users were more likely to be obese, diagnosed with T2D for a longer duration, and female as compared to those prescribed SGLT-2 inhibitors