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L'tude montre que le taux d'activit, bien que fluctueux, reste en dessous des valeurs observes sur les rats tmoins qui ont reu une injection de phnobarbital, activateur de cytochrome P-450, ce qui indique que les matriaux ne sont pas mtaboliss par voie Cyp450, en concordance avec la polarit importante des ligands dicarboxyliques .In the toxicity tests, careful observation of the animals revealed no apparent sign of harmfulness of the injected material