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CMAJ 2023;195:E63949

So UPFs come into the marketplace somewhere in the mid-60s and the firms are operating at scale by the 1980s as the obesity rates in America start to tick up and they keep going up, up, up as ultra-processed foods continue to penetrate our food supply

However, if it happens regularly despite adjustments, you should reduce nicotine or consult a healthcare professional

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If you want a different amount of nicotine base, we advise you to use an online DIY calculator