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3.Is it worse to smoke than vape

Prior work from our lab has demonstrated that even in the absence of caustic smoking-related stimuli, TCCSUP cell-derived EVs can promote the malignant transformation of immortalized human urothelial SV-HUC cells in a cargo protein-dependent manner 40

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Negative Mood Effects: While some individuals often use tobacco to alleviate stress or improve mood temporarily, long-term tobacco use leads to mood disturbances and irritability, particularly during periods of nicotine withdrawal

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