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Clear clinical implications, but gaps in available knowledge In view of the analysis and synthesis presented in this study, the authors highlight the need to re-evaluate the degree of lesser harmfulness of the electronic cigarette compared to the cigarette because the scientific assertion that the electronic cigarette would be 95% less harmful than the cigarette, put forward by the Public Health England and the Royal College of Physicians is clearly not in line with reality

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People with moderate or high levels of psychological distress are at least as likely as anyone else to report wanting to quit smoking, trying to quit smoking, and using smoking cessation aids