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News outlets followed the research teams lead in speculating a topical SIKi could help protect against skin cancer

Figure 4 MOS enhances IGF-1/PI3K/mTOR pathway activity and reduces apoptosis in model mice In the Model group, protein expression of p-mTOR/mTOR, p-Akt/Akt, p-PI3K/PI3K, Bcl-2, and IGF-1 was significantly reduced, whereas Cleaved Caspase-3 was increased

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Reflecting its 44-amino acid backbone plus the N-terminal trans-3-hexenoic acid conjugate