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Both are heavyweight antioxidants, but they play distinct roles in the body

doi: 10.1007/978-3-031-00793-4_1 142 BatchuluunBPinkoskySLSteinbergGR

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In addition, ARNTL2 knockdown decreases N-cadherin expression and increases the expression of -catenin and E-cadherin in lung adenocarcinoma cells, while the opposite effects are observed in ARNTL2-overexpressed cells, 118 suggesting that ARNTL2 overexpression may promote EMT by inhibiting ferroptosis