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[8] That said, researchers did not observe change in the frequency of GH pulses or levels of IGF-I, IGF binding protein-3 (IGFBP-3), or GH binding protein (GHBP)

Various pathophysiologic changes are associated with ischemic stroke, including glutamate excitotoxicity, neuroinflammation, BBB disruption, oxidative stress, mitochondrial dysfunction, and cell death[54]