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Gastroenterology 154, 21782193

Batch nanoparticle synthesis methods lack control in particle growth, mixing, and separation to prevent agglomeration, ultimately causing fluctuations in size distribution and a diverse particle assortment with varying chemical and physical traits, which restricts the synthesis of coreshell nanoparticles and diminishes encapsulation efficiencies (EE)

Severe Stomach Problems The most common side effect of Ozempic is gastrointestinal upset, which includes stomach ache, nausea, diarrhea, vomiting, and loss of appetite

In addition, the compound did not trigger the nausea, malaise and gastrointestinal adverse effects commonly seen with many first-generation GLP-1 therapies, a distinction that could become increasingly significant as patient populations and adherence demands grow