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Mechanistic Comparison# Dosing Comparison# MariTide Dosing# MariTide is administered as a once-monthly subcutaneous injection -- the longest dosing interval of any obesity medication in development

evidence strength varies by component

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External resources SUSTAIN-6 Trial - New England Journal of Medicine : The landmark cardiovascular outcomes trial showing 26% MACE reduction with semaglutide in high-risk type 2 diabetes patients, providing foundational evidence for semaglutide cardiovascular benefit