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Rebouche CJ, Seim H (1998)
4.6 Antitumor effects 4.6.1 Induction of tumor cell apoptosis The antitumor properties of GPS have been extensively studied across multiple cancer cell lines, such as those derived from human lung, breast, and liver cancers
Balances concentration with syringe precision | | 50mg | 5mL | 10mg/mL | 0.5mL (50 units) | 1.0mL (100 units) | Lower concentration improves measurement accuracy but uses solution faster | | 100mg | 2mL | 50mg/mL | 0.1mL (10 units) | 0.2mL (20 units) | Higher vial amount extends total doses but requires same precision as 50mg/1mL | | 100mg | 4mL | 25mg/mL | 0.2mL (20 units) | 0.4mL (40 units) | Optimal for multi-week protocols
Several laboratory tests should be performed prior to treatment with cyanocobalamin, including serum vitamin B12, folate, iron, hematocrit, and reticulocyte count