Increased fat synthesis based on enhanced glycolytic activity (pklr1, sterol regulatory element-binding protein-1 [SREBP1c], fas, and liver X receptor a [lxra]) in aged mice partly accounted for hepatic steatosis (increased leukocytic infiltration) and necrosis (increased plasma aspartate aminotransferase [AST] activity), compared with reduced srebp1c and fas mRNA levels in young mice
Nanotechnology 32 (36), 365101
Synthesized as secondary metabolites or protein metabolism byproducts, CDPs are produced via CDP synthases and non-ribosomal peptide synthetases (NRPSs), utilizing aminoacyl-tRNAs as substrates, with additional modifications by tailoring enzymes (Fizza et al., 2025)
Murphy and George Minot for discovery of an effective treatment for pernicious anemia using liver concentrate, later found to contain a large amount of vitamin B 12
In addition to serotonin, dopamine is another neurotransmitter significantly affected by chronic ethanol consumption