Furthermore, most of the available evidence is derived from preclinical animal models, which may not fully replicate human pathophysiology
(2013) Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target
The variant allele 718C of the GPX4 gene was found to be significantly associated with an increased risk of CS in hypertensive patients (odds ratio (OR) 1.53, 95% confidence interval (CI) 1.231.90, P adj =0.0003)
The effectiveness of immunotherapies relies on the ability of immune cells to reach, infiltrate, and kill cancer cells, features that conventional in vitro cultures and animal models fail to accurately reproduce
[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Cheng S.B., Liu H.T., Chen S.Y., Lin P.T., Lai C.Y., Huang Y.C