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A Root Cause Medicine Approach: A Comprehensive Guide On How To Test For Low Nitric Oxide Levels

doi: 10.1016/S1569-9056(02)80120-8 127 KruecklSLSikesRAEdlundNMBellRHHurtado-CollAFazliLet al

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in vitro experiments demonstrated that SGK1 knockdown attenuated erastin-induced downregulation of Slc7a11, GPX4, GSH, and oxidized glutathione (GSSG), while reducing lipid peroxidation, iron accumulation, and mitochondrial damage upregulation, suggesting SGK1's critical role in CHD-associated ferroptosis (44)