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A population-based study in 3,884 elderly men and women with depressive disorders found that those with vitamin B 12 deficiency were almost 70% more likely to experience depression than those with normal vitamin B 12 status (98)

It is highly recommended that those with MTHFR take supplements that contain one or more of the active forms of B12 (methylcobalamin, hydroxocobalamin and/or adenosylcobalamin) along with the active folate form, methylfolate

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Gut healing applications may show results within the first 2-4 weeks