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Human LR3 IGF-I (Receptor Grade) Human LR3 insulin-like Growth Factor-I (LR3IGF-I) is an 83 amino acid analogue of IGF-I comprising the complete human IGF-I sequence with the substitution of an Arginine for the Glutamine at position 3, plus a 13 amino acid extension peptide at the N-terminus

[1] The TIM barrel contains the active site, all catalytic residues, and a Ca 2+ binding site

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Journal of Clinical Endocrinology & Metabolism , 2006 Demonstrated sustained GH and IGF-1 elevation with CJC-1295

Indeed, GLP-1 and analogues are known to form amphipathic -helix structures that are poorly soluble and prone to generate aggregates 33