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Moreover, in order to clarify the previously proposed methodological problems of abstainers misclassification, sick quitter hypothesis, and potentially confounding factors 17 , we categorized drinking status of ex-drinkers into regular drinker to avoid misclassifying the former drinkers as abstainers and controlled 15 confounders to minimize confounding

Tobacco smoke can induce metalloproteinase MMP-1, an enzyme that can break down collagen, decreasing skin elasticity

Up until 2006 when the FIA banned tobacco advertising, billions of dollars were pumped into motorsports in exchange for banners and liveries

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