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It also protects the neurons from neurotoxicity and stabilized the Ca 2+ homeostasis and IGF-1 expression

Moreover, dysbiosis increases the production of ROS within cells through various mechanisms, including mitochondrial dysfunction, activation of NADPH oxidases, and inhibition of antioxidant enzymes (57)

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Assuming that the lower temperature (20 C) enhanced glutathione biosynthesis in batch fermentation and hindered cell growth in the fed-batch system, the culture temperature was increased to 30 Cthe optimal growth temperature for S