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Guarana is a Brazilian climbing plant whose seeds naturally contain caffeine in a plant matrix that releases more slowly than isolated caffeine powder

Each cohort was then treated for 14 consecutive days with twice-daily treatments with either 300 mg/kg of NHPN-1010 or an equivalent volume of saline

Individuals dealing with anxiety during recovery may also experience elevated cortisol that compounds the problem

For most adults and older children, the soreness lessens within a few days

All experiments with animals were performed in accordance with institutional guidelines approved by the Institutional Animal Care and Use Committee (IACUC) at the University of Pittsburgh School of Medicine