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The problem is that patients dont want to argue with doctors, they dont want to challenge what they have been advised, they think doctor knows best

Interestingly, we observed a modest increase in PCK1 expression in Caco-2 cells and the colon, although not statistically significant in the latter, implying that gluconeogenic responses may vary between the ileum and colon

Additionally, dysregulation of key neurotransmitters, such as elevated noradrenaline and reduced serotonin, particularly within the amygdala, has been implicated in heightened anxiety and impaired stress resilience (112, 113)

the side-effect burdens of pharmacotherapy and possible drug interactions

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