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Until now, only one, older RCT compared the efficacy on sleep onset latency according to melatonin dosage [18]

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Activity of the ventral striatum and OFC is decreased in anhedonic individuals with MDD or schizophrenia (The neural correlates of anhedonia in major depressive disorder,2005), although it is debated whether schizophrenia is associated with impaired reward valuation and motivation rather than decreased hedonic capacity

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Development Background Cagrilintide was developed by Novo Nordisk as part of its efforts to explore novel peptide-based approaches for metabolic studies