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To date, only one study (Sasaninezhad et al., 2024) reported outcomes at a 3-month follow-up, but its small sample size limits the generalizability of these findings

Tirzepatide, the dual GLP-1/GIP receptor agonist, is available as a weekly injection starting at $289 monthly or as an oral formulation at $349 monthly

For therapeutics this means: native human amylin cannot be administered as a drug, it aggregates already in the syringe and in the subcutis

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All except one of the six genetic studies considered Hardy Weinberg equilibrium [47, 50, 94, 96, 97], two provided power calculations [96, 97] and two adjusted for multiple comparisons [50, 97] (although a footnote indicating that the associations were no longer statistically significant was not added in one case) [50]